|Other Accession||NM_015589, NP_056404|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog|
|Alias Symbol||DKFZp434H0350, KIAA1053, SAMD4, SMG, SMGA, Smaug, Smaug1, SMAUG, SMAUG1|
|Other Names||Protein Smaug homolog 1, Smaug 1, hSmaug1, Sterile alpha motif domain-containing protein 4A, SAM domain-containing protein 4A, SAMD4A, KIAA1053, SAMD4, SMAUG1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SAMD4A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SAMD4A antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1053, SAMD4, SMAUG1|
|Function||Acts as a translational repressor of SRE-containing messengers.|
|Cellular Location||Cytoplasm. Cell projection, dendrite. Cell junction, synapse, synaptosome. Note=Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1.|
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Provided below are standard protocols that you may find useful for product applications.
Heilig R.,et al.Nature 421:601-607(2003).
Guo J.H.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Baez M.V.,et al.J. Biol. Chem. 280:43131-43140(2005).
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