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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   TEX14 antibody - C-terminal region   

TEX14 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - TEX14 antibody - C-terminal region AI13628

    WB Suggested Anti-TEX14 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human Muscle
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IWB6
Other Accession NM_031272, NP_112562
Reactivity Human, Rat, Rabbit, Horse
Predicted Human, Rabbit, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 160kDa
Additional Information
Gene ID 56155
Alias Symbol CT113
Other Names Inactive serine/threonine-protein kinase TEX14, Protein kinase-like protein SgK307, Sugen kinase 307, Testis-expressed sequence 14, Testis-expressed sequence 14 protein, TEX14, SGK307
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TEX14 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTEX14 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TEX14
Synonyms SGK307
Function Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity).
Cellular Location Cytoplasm. Midbody. Chromosome, centromere, kinetochore Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division.
Tissue Location Detected in testis.
Research Areas
Citations (0)

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Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Wang P.J.,et al.Nat. Genet. 27:422-426(2001).
Wu M.-H.,et al.Gene Expr. Patterns 3:231-236(2003).
Iwamori T.,et al.Mol. Cell. Biol. 30:2280-2292(2010).

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$ 293.00
Cat# AI13628
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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