|Other Accession||NM_001042646, NP_001036111|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||OIP106, MILT1|
|Other Names||Trafficking kinesin-binding protein 1, 106 kDa O-GlcNAc transferase-interacting protein, TRAK1, KIAA1042, OIP106|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TRAK1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TRAK1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.|
|Cellular Location||Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Note=Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HRS. Colocalizes with MGARP at the mitochondria|
|Tissue Location||High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined|
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Provided below are standard protocols that you may find useful for product applications.
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Iyer S.P.N.,et al.J. Biol. Chem. 278:5399-5409(2003).
Brickley K.,et al.J. Biol. Chem. 280:14723-14732(2005).
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