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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rpsa antibody - N-terminal region   

Rpsa antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Rpsa antibody - N-terminal region AI13668

    WB Suggested Anti-Rpsa Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14206
Other Accession NM_011029, NP_035159
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog
Predicted Human, Mouse, Sheep, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 32kDa
Additional Information
Gene ID 16785
Alias Symbol 67kDa, 67lr, AL022858, Lamr, Lamr1, Lamrl1, MGC117921, MGC118614, MLR, P40, P40-3, P40-8
Other Names 40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}, 37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}, 37LRP {ECO:0000255|HAMAP-Rule:MF_03016}, 37 kDa oncofetal antigen, 37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}, 67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, 67LR {ECO:0000255|HAMAP-Rule:MF_03016}, Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}, LamR {ECO:0000255|HAMAP-Rule:MF_03016}, Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}, LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}, OFA/iLRP, Rpsa, Lamr1, P40-8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rpsa antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRpsa antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rpsa
Synonyms Lamr1, P40-8
Function Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity). Enables malignant tumor cells to penetrate laminin tissue and vessel barriers. Activates precursor thymic anti- OFA/iLRP specific cytotoxic T-cell. May induce CD8 T-suppressor cells secreting IL-10.
Cellular Location Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C- terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus. Colocalizes with PPP1R16B in the cell membrane (By similarity). 37LRP shuttles to the nucleus upon midkine (MDK) binding. {ECO:0000255|HAMAP-Rule:MF_03016}
Research Areas
Citations (0)

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Rao C.N.,et al.Biochemistry 28:7476-7486(1989).
Makrides S.,et al.Nucleic Acids Res. 16:2349-2349(1988).
Coggin J.H. Jr.,et al.Anticancer Res. 19:5535-5542(1999).
Lee I.Y.,et al.Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).

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$ 293.00
Cat# AI13668
Availability: 2-3 days
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