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Frg1 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Frg1 antibody - middle region AI13677

    WB Suggested Anti-Frg1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Mouse Brain
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P97376
Other Accession NM_013522, NP_038550
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Goat, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 14300
Other Names Protein FRG1, FSHD region gene 1 protein, Frg1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Frg1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFrg1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Frg1
Function Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B.
Cellular Location Nucleus, Cajal body {ECO:0000250|UniProtKB:Q14331}. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Note=Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytoplasmic 5 days post-differentiation. Localized at the Z-line in the sarcomere of matured myotubes 8 days post-differentiation
Citations (0)
citation

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References

Grewal P.K.,et al.Gene 216:13-19(1998).
Carninci P.,et al.Science 309:1559-1563(2005).
Gabellini D.,et al.Nature 439:973-977(2006).
Hanel M.L.,et al.Differentiation 81:107-118(2011).
Neguembor M.V.,et al.J. Mol. Cell Biol. 5:294-307(2013).

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$ 389.00
Cat# AI13677
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