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HIST1H1T antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P22492 |
| Other Accession | NM_005323, NP_005314 |
| Reactivity | Human, Rabbit, Pig, Dog |
| Predicted | Human, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 22kDa |
| Gene ID | 3010 |
|---|---|
| Alias Symbol | H1FT, H1t, MGC163222, dJ221C16.2 |
| Other Names | Histone H1t, Testicular H1 histone, HIST1H1T, H1FT, H1T |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HIST1H1T antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | HIST1H1T antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | H1-6 (HGNC:4720) |
|---|---|
| Function | Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes (PubMed:26757249). Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination (PubMed:26757249). Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration (Probable). |
| Cellular Location | Nucleus. Chromosome. |
| Tissue Location | Testis-specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Drabent B.,et al.Gene 103:263-268(1991).
Koppel D.A.,et al.J. Cell. Biochem. 54:219-230(1994).
Marzluff W.F.,et al.Genomics 80:487-498(2002).
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