|Other Accession||NM_012121, NP_036253|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Bovine, Dog|
|Alias Symbol||BORG4, CEP4, KAIA1777, MGC17125, MGC3740|
|Other Names||Cdc42 effector protein 4, Binder of Rho GTPases 4, CDC42EP4, BORG4, CEP4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CDC42EP4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CDC42EP4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues|
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Provided below are standard protocols that you may find useful for product applications.
Osada N.,et al.J. Hum. Genet. 45:374-377(2000).
Hirsch D.S.,et al.J. Biol. Chem. 276:875-883(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Olsen J.V.,et al.Cell 127:635-648(2006).
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