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Mfsd7b antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Mfsd7b antibody - middle region AI13723

    WB Suggested Anti-Mfsd7b Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession B2RXV4
Other Accession NM_001081259, NP_001074728
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 60kDa
Additional Information
Gene ID 226844
Alias Symbol 9630055N22Rik, FLVCR, Flvcr1
Other Names Feline leukemia virus subgroup C receptor-related protein 1, Feline leukemia virus subgroup C receptor, Major facilitator superfamily domain containing 7B, Mfsd7b, Flvcr1, Mfsd7b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Mfsd7b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMfsd7b antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Flvcr1
Synonyms Mfsd7b
Function Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro (By similarity). Required during erythtopoiesis to maintain intracellular free heme balance since in proerythroblasts, heme synthesis intensifies and it's accumulation is toxic for cells.
Cellular Location Isoform 1: Cell membrane; Multi-pass membrane protein
Citations (0)

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Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Keel S.B.,et al.Science 319:825-828(2008).
Chiabrando D.,et al.J. Clin. Invest. 122:4569-4579(2012).

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$ 293.00
Cat# AI13723
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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