FTSJD2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application
| WB |
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Primary Accession | Q8N1G2 |
Other Accession | NM_015050, NP_055865 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 95kDa |
Gene ID | 23070 |
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Alias Symbol | KIAA0082, MTr1, hMTr1, FTSJD2 |
Other Names | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, 2.1.1.57, Cap methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1, hMTr1, FtsJ methyltransferase domain-containing protein 2, Interferon-stimulated gene 95 kDa protein, ISG95, CMTR1, FTSJD2, KIAA0082, MTR1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-FTSJD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | FTSJD2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CMTR1 |
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Synonyms | FTSJD2, KIAA0082, MTR1 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ohara O.,et al.Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Geiss G.K.,et al.J. Virol. 77:6367-6375(2003).
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