|Other Accession||NM_015050, NP_055865|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||KIAA0082, MTr1, hMTr1, FTSJD2|
|Other Names||Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, 188.8.131.52, Cap methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1, hMTr1, FtsJ methyltransferase domain-containing protein 2, Interferon-stimulated gene 95 kDa protein, ISG95, CMTR1, FTSJD2, KIAA0082, MTR1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-FTSJD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FTSJD2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FTSJD2, KIAA0082, MTR1|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.|
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Provided below are standard protocols that you may find useful for product applications.
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ohara O.,et al.Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Geiss G.K.,et al.J. Virol. 77:6367-6375(2003).
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