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Anks1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • IP - Anks1 antibody - C-terminal region AI13762
    Amount and Sample Type : HeLa lysate Amount of IP Antibody : 10ug Primary Antibody : Anks1
    Primary Antibody Dilution : 1:1000
    Secondary Antibody : Goat anti-rabbit-HRP Secondary Antibody Dilution : 1:5000
    Gene Name : Anks1 Submitted by : Barbara Woller; Medical University of Vienna
  • WB - Anks1 antibody - C-terminal region AI13762

    WB Suggested Anti-Anks1 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q68FS2
Other Accession NM_001004275, NP_001004275
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 127kDa
Additional Information
Gene ID 360915
Alias Symbol Anks1a, MGC59413, mKIAA0229
Other Names COP9 signalosome complex subunit 4, SGN4, Signalosome subunit 4, JAB1-containing signalosome subunit 4, Cops4, Csn4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Anks1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAnks1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cops4
Synonyms Csn4
Function Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).
Cellular Location Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
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Granata A.,et al.EMBO J. 30:181-193(2011).

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$ 293.00
Cat# AI13762
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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