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> home > Products > Primary Antibodies > Signal Transduction > Traf3ip1 antibody - N-terminal region
Traf3ip1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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Application 
| WB |
|---|---|
| Primary Accession | Q149C2 |
| Other Accession | NM_028718, NP_082994 |
| Reactivity | Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 69kDa |
| Gene ID | 74019 |
|---|---|
| Alias Symbol | 3930402D05Rik, AU041749, MGC143957, MIP-T3 |
| Other Names | TRAF3-interacting protein 1, Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3, Traf3ip1, Ift54, Mipt3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Traf3ip1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Traf3ip1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Traf3ip1 |
|---|---|
| Synonyms | Ift54, Mipt3 |
| Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity). Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268). Involved in ciliogenesis (PubMed:21945076). |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8TDR0}. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Microtubules. In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip. {ECO:0000250|UniProtKB:Q8TDR0} |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Ma B.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Follit J.A.,et al.Cell Motil. Cytoskeleton 66:457-468(2009).
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$ 389.00
Cat# AI13778
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