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PHACTR1 antibody - middle region

Rabbit Polyclonal Antibody

     
  • IHC - PHACTR1 antibody - middle region AI13789
    Immunohistochemistry with Human Tonsil lysate tissue at an antibody concentration of 5.0μg/ml using anti-PHACTR1 antibody (AI13789)
    detail
  • WB - PHACTR1 antibody - middle region AI13789

    WB Suggested Anti-PHACTR1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q9C0D0
Other Accession NM_030948, NP_112210
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 66kDa
Additional Information
Gene ID 221692
Alias Symbol KIAA1733, MGC126575, MGC126577, RPEL, RPEL1, dJ257A7.2
Other Names Phosphatase and actin regulator 1, PHACTR1, KIAA1733, RPEL1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PHACTR1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPHACTR1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHACTR1
Synonyms KIAA1733, RPEL1
Function Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (PubMed:21798305, PubMed:21939755). Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity).
Cellular Location Cytoplasm. Synapse. Nucleus. Note=Enriched at synapses (By similarity) Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity).
Tissue Location Detected in umbilical vein endothelial cells.
Research Areas
Citations (0)
citation

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References

Nagase T.,et al.DNA Res. 7:347-355(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Jarray R.,et al.Biochimie 93:1668-1675(2011).
Allain B.,et al.Cell. Signal. 24:214-223(2012).

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$ 389.00
Cat# AI13789
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