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HOM-TES-103 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q0D2I5 |
| Other Accession | NM_080731, NP_542769 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23kDa |
| Gene ID | 25900 |
|---|---|
| Alias Symbol | DKFZp586I2223, FLJ20703, HOM-TES-103, IFFO, MGC117359 |
| Other Names | Intermediate filament family orphan 1, Tumor antigen HOM-TES-103, IFFO1, IFFO |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HOM-TES-103 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | HOM-TES-103 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IFFO1 (HGNC:24970) |
|---|---|
| Synonyms | IFFO |
| Function | Nuclear matrix protein involved in the immobilization of broken DNA ends and the suppression of chromosome translocation during DNA double-strand breaks (DSBs) (PubMed:31548606). Interacts with the nuclear lamina component LMNA, resulting in the formation of a nucleoskeleton that relocalizes to the DSB sites in a XRCC4-dependent manner and promotes the immobilization of the broken ends, thereby preventing chromosome translocation (PubMed:31548606). Acts as a scaffold that allows the DNA repair protein XRCC4 and LMNA to assemble into a complex at the DSB sites (PubMed:31548606). |
| Cellular Location | Nucleus. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus matrix. Note=Mainly soluble, the remaining is localized in the nuclear matrix (PubMed:31548606). Localized at double- strand break (DSB) sites near the lamina and nuclear matrix structures (PubMed:31548606). |
| Tissue Location | Ubiquitously expressed. |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI13793
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