Fam123a antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8CCJ4 |
Other Accession | NM_028113, NP_082389 |
Reactivity | Human, Mouse, Rat, Rabbit |
Predicted | Rabbit, Chicken |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 66kDa |
Gene ID | 72125 |
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Alias Symbol | 2600011E07Rik, Amer2, Fam123a |
Other Names | APC membrane recruitment protein 2, Amer2, Protein FAM123A, Amer2, Fam123a |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Fam123a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Fam123a antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Amer2 |
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Synonyms | Fam123a |
Function | Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity). |
Cellular Location | Cell membrane; Peripheral membrane protein. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. |
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