|Other Accession||NM_173827, NP_776188|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Bovine, Guinea Pig, Dog|
|Alias Symbol||COX18HS, FLJ38991, MGC126733|
|Other Names||Mitochondrial inner membrane protein COX18, COX18Hs, Cytochrome c oxidase assembly protein 18, COX18, OXA1L2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-COX18 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||COX18 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Sacconi S.,et al.Biochem. Biophys. Res. Commun. 337:832-839(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gaisne M.,et al.FEMS Yeast Res. 6:869-882(2006).
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