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Cyp4x1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q6A152 |
| Other Accession | NM_001003947, NP_001003947 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58kDa |
| Gene ID | 81906 |
|---|---|
| Alias Symbol | A230025G20, CYP_a, Cyp4a28-ps |
| Other Names | Cytochrome P450 4X1, 1.14.14.1, CYPIVX1, Cyp4x1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Cyp4x1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Cyp4x1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Cyp4x1 {ECO:0000303|PubMed:16478468, ECO:0000312|MGI:MGI:1932403} |
|---|---|
| Function | A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein |
| Tissue Location | Expressed in brain and aorta. In the brain, expressed in the Purkinje cells of the cerebellum, pyramidal neurons in the dentate gyrus of the hippocampus, cortical forebrain neurons and those of brain stem nuclei (at protein level). In addition to neurons, also expressed in cerebral vascular endothelial cells (at protein level). Also expressed in epithelial cells of the choroid plexus (at protein level). Hardly detectable in heart, lung, kidney and spleen |
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Al-Anizy M.,et al.FEBS J. 273:936-947(2006).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Carninci P.,et al.Science 309:1559-1563(2005).
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$ 389.00
Cat# AI13848
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