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Amigo2 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q7TNJ4 |
| Other Accession | NM_182816, NP_877968 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Mouse, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57kDa |
| Gene ID | 300186 |
|---|---|
| Alias Symbol | Ali1, Amigo2 |
| Other Names | Amphoterin-induced protein 2, AMIGO-2, Alivin-1, Amigo2 {ECO:0000312|EMBL:AAO48951.1} |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Amigo2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Amigo2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Amigo2 {ECO:0000312|EMBL:AAO48951.1} |
|---|---|
| Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Nucleus Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons |
| Tissue Location | Highest levels in the lung. High levels in cerebellar granule neurons and Purkinje cells. Also in pyramidal cells between CA1 and CA3 regions of the hippocampus and granule cells of the dentate gyrus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Kuja-Panula J.,et al.J. Cell Biol. 160:963-973(2003).
Ono T.,et al.J. Neurosci. 23:5887-5896(2003).
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