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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   2610034B18Rik antibody - N-terminal region   

2610034B18Rik antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - 2610034B18Rik antibody - N-terminal region AI13861

    WB Suggested Anti-2610034B18Rik Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Spleen
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9D0A3
Other Accession NM_027420, NP_081696
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Additional Information
Gene ID 70420
Other Names Arpin, Arp2/3 inhibition protein, Arpin
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-2610034B18Rik antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
Precautions2610034B18Rik antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Arpin
Function Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence (By similarity).
Cellular Location Cell projection, lamellipodium. Note=Colocalized with the WAVE complex at lamellipodium tip
Research Areas
Citations (0)

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Carninci P.,et al.Science 309:1559-1563(2005).
Dang I.,et al.Nature 503:281-284(2013).

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$ 293.00
Cat# AI13861
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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