Plcb1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9Z1B3 |
Other Accession | NM_001145830, NP_001139302 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 133kDa |
Gene ID | 18795 |
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Alias Symbol | 3110043I21Rik, AI132408, Plcb, mKIAA0581 |
Other Names | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-1, 3.1.4.11, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-beta-1, PLC-beta-1, Plcb1, Plcb |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Plcb1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Plcb1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Plcb1 {ECO:0000312|MGI:MGI:97613} |
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Synonyms | Plcb |
Function | Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5- bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein- coupled receptors (PubMed:27653213). Regulates the function of the endothelial barrier (PubMed:27653213). |
Cellular Location | Nucleus membrane. Cytoplasm {ECO:0000250|UniProtKB:P10687}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. |
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Provided below are standard protocols that you may find useful for product applications.
References
Bai J.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Ehringer M.A.,et al.Mamm. Genome 12:657-663(2001).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Watanabe M.,et al.Eur. J. Neurosci. 10:2016-2025(1998).
Dupont G.,et al.Biochem. J. 316:583-591(1996).
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