|Other Accession||NM_001145830, NP_001139302|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||3110043I21Rik, AI132408, Plcb, mKIAA0581|
|Other Names||1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-1, 22.214.171.124, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-beta-1, PLC-beta-1, Plcb1, Plcb|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Plcb1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Plcb1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.|
|Cellular Location||Nucleus membrane. Cytoplasm Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes|
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Provided below are standard protocols that you may find useful for product applications.
Bai J.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Ehringer M.A.,et al.Mamm. Genome 12:657-663(2001).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Watanabe M.,et al.Eur. J. Neurosci. 10:2016-2025(1998).
Dupont G.,et al.Biochem. J. 316:583-591(1996).
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