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TBC1D10C antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8IV04 |
| Other Accession | NM_198517, NP_940919 |
| Reactivity | Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50kDa |
| Gene ID | 374403 |
|---|---|
| Alias Symbol | FLJ00332, MGC46488, EPI64C, CARABIN |
| Other Names | Carabin, TBC1 domain family member 10C, TBC1D10C |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TBC1D10C antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TBC1D10C antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TBC1D10C |
|---|---|
| Function | Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. |
| Tissue Location | Most abundant in spleen and peripheral blood leukocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Pan F.,et al.Nature 445:433-436(2007).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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