|Other Accession||NM_198517, NP_940919|
|Reactivity||Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||FLJ00332, MGC46488, EPI64C, CARABIN|
|Other Names||Carabin, TBC1 domain family member 10C, TBC1D10C|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TBC1D10C antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TBC1D10C antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.|
|Tissue Location||Most abundant in spleen and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Pan F.,et al.Nature 445:433-436(2007).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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