Blmh Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8R016 |
Other Accession | NM_178645, NP_848760 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Gene ID | 104184 |
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Alias Symbol | AI035728, Bh, Bmh |
Other Names | Bleomycin hydrolase, BH, BLM hydrolase, BMH, 3.4.22.40, Blmh |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Blmh antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Blmh Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Blmh |
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Function | The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q13867}. Cytoplasmic granule {ECO:0000250|UniProtKB:Q13867}. Note=Co-localizes with NUDT12 in the cytoplasmic granules {ECO:0000250|UniProtKB:Q13867} |
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Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Park J.,et al.Mol. Cell 50:919-930(2013).
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