|Other Accession||NM_001015055, NP_001015055|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Other Names||Rhotekin, RTKN (HGNC:10466), RTKN1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RTKN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RTKN antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.|
|Tissue Location||Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
Fu Q.,et al.Genomics 66:328-332(2000).
Reynaud C.,et al.J. Biol. Chem. 275:33962-33968(2000).
Hillier L.W.,et al.Nature 434:724-731(2005).
Liu C.-A.,et al.Oncogene 23:8731-8742(2004).
Ito H.,et al.Oncogene 24:7064-7072(2005).
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