|Other Accession||NM_002835, NP_002826|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||PTP-PEST, PTPG1|
|Other Names||Tyrosine-protein phosphatase non-receptor type 12, 22.214.171.124, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1, PTPN12|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PTPN12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PTPN12 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.|
|Cellular Location||Cytoplasm. Cell projection, podosome|
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Provided below are standard protocols that you may find useful for product applications.
Takekawa M.,et al.Biochem. Biophys. Res. Commun. 189:1223-1230(1992).
Yang Q.,et al.J. Biol. Chem. 268:6622-6628(1993).
Yang Q.,et al.J. Biol. Chem. 268:17650-17650(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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