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Rab27b antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q99P58 |
| Other Accession | NM_030554, NP_085031 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Mouse, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24kDa |
| Gene ID | 80718 |
|---|---|
| Alias Symbol | 2310021G14Rik, B130064M09Rik |
| Other Names | Ras-related protein Rab-27B, Rab27b |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Rab27b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Rab27b antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Rab27b |
|---|---|
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (By similarity). Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (By similarity). May be involved in targeting uroplakins to urothelial apical membranes (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:O00194}; Lipid- anchor {ECO:0000250|UniProtKB:O00194}. Late endosome {ECO:0000250|UniProtKB:O00194} |
| Tissue Location | Expressed abundantly in the stomach and is predominantly localized at the apical region of gastric-surface mucus cells. Also expressed in the brain and spleen |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Ramalho J.S.,et al.BMC Genet. 2:2-2(2001).
Chen Y.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Zhao S.,et al.Endocrinology 143:1817-1824(2002).
Fukuda M.,et al.J. Biol. Chem. 277:43096-43103(2002).
Fukuda M.,et al.J. Biol. Chem. 278:15373-15380(2003).
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