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SCO1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - SCO1 Antibody - C-terminal region AI13969

    Host: Rabbit
    Target Name: SCO1
    Sample Tissue: Large intestine Tumor lysates
    Antibody Dilution: 1.0μg/ml
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O75880
Reactivity Human
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 6341
Alias Symbol SCO1, SCOD1,
Other Names Protein SCO1 homolog, mitochondrial, SCO1, SCOD1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-SCO1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSCO1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCO1
Synonyms SCOD1
Function Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT- CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (PubMed:15659396, PubMed:16735468, PubMed:17189203, PubMed:19336478, PubMed:15229189). Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity).
Cellular Location Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein
Tissue Location Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.
Research Areas
Citations (0)
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References

Petruzzella V.,et al.Genomics 54:494-504(1998).
Horvath R.,et al.Biochem. Biophys. Res. Commun. 276:530-533(2000).
Peng Y.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 389.00
Cat# AI13969
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