|Other Accession||NM_011056, NP_035186|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse|
|Alias Symbol||9630011N22Rik, Dpde3|
|Other Names||cAMP-specific 3', 5'-cyclic phosphodiesterase 4D, 18.104.22.168, DPDE3, Pde4d|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Pde4d antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Pde4d antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.|
|Cellular Location||Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Apical cell membrane Note=Colocalized with SHANK2 to the apical membrane of colonic crypt cells (By similarity). Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome.|
|Tissue Location||Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis|
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Provided below are standard protocols that you may find useful for product applications.
Wang D.,et al.Cell. Signal. 15:883-891(2003).
Chai H.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Repaske D.R.,et al.J. Biol. Chem. 267:18683-18688(1992).
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