|Other Accession||NM_011056, NP_035186|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse|
|Alias Symbol||9630011N22Rik, Dpde3|
|Other Names||cAMP-specific 3', 5'-cyclic phosphodiesterase 4D, 188.8.131.52, DPDE3, Pde4d|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Pde4d antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Pde4d antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.|
|Cellular Location||Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Apical cell membrane Note=Colocalized with SHANK2 to the apical membrane of colonic crypt cells (By similarity). Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome.|
|Tissue Location||Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Wang D.,et al.Cell. Signal. 15:883-891(2003).
Chai H.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Repaske D.R.,et al.J. Biol. Chem. 267:18683-18688(1992).
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