Pde4d antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q01063 |
Other Accession | NM_011056, NP_035186 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 84kDa |
Gene ID | 238871 |
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Alias Symbol | 9630011N22Rik, Dpde3 |
Other Names | cAMP-specific 3', 5'-cyclic phosphodiesterase 4D, 3.1.4.53, DPDE3, Pde4d |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Pde4d antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Pde4d antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Pde4d |
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Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
Cellular Location | Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Apical cell membrane. Note=Colocalized with SHANK2 to the apical membrane of colonic crypt cells (By similarity). Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome. |
Tissue Location | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis |
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Provided below are standard protocols that you may find useful for product applications.
References
Wang D.,et al.Cell. Signal. 15:883-891(2003).
Chai H.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Repaske D.R.,et al.J. Biol. Chem. 267:18683-18688(1992).
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