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Lap3 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Lap3 antibody - N-terminal region AI13998

    WB Suggested Anti-Lap3 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9CPY7
Other Accession NM_024434, NP_077754
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Rabbit, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 66988
Alias Symbol 2410015L10Rik, AA410100, Lap, Lapep, Pep-7, Pep-S, Pep7, Peps, LAP-3
Other Names Cytosol aminopeptidase, 3.4.11.1, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, Proline aminopeptidase, 3.4.11.5, Prolyl aminopeptidase, Lap3, Lapep
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Lap3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLap3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lap3 {ECO:0000312|MGI:MGI:1914238}
Synonyms Lapep
Function Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S- conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}.
Research Areas
Citations (0)
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References

Zhuang D.Z.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Lubec G.,et al.Submitted (APR-2007) to UniProtKB.
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).

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$ 389.00
Cat# AI13998
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