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Cdk5rap1 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Cdk5rap1 antibody - C-terminal region AI14029

    WB Suggested Anti-Cdk5rap1 Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9JLH6
Other Accession NM_145721, NP_663773
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 65kDa
Additional Information
Gene ID 252827
Alias Symbol Cdk5rap1
Other Names CDK5 regulatory subunit-associated protein 1, CDK5 activator-binding protein C42, Cdk5rap1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Cdk5rap1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCdk5rap1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cdk5rap1
Function Methylthiotransferase that catalyzes the conversion of N6- (dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp) (By similarity). Essential for efficient and highly accurate protein translation by the ribosome (By similarity). Specifically inhibits CDK5 activation by CDK5R1 (By similarity). Essential for efficient mitochondrial protein synthesis and respiratory chain (By similarity).
Cellular Location Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q96SZ6}
Tissue Location Expressed in brain..
Citations (0)
citation

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References

Ching Y.-P.,et al.Gene 242:285-294(2000).
Ching Y.-P.,et al.J. Biol. Chem. 277:15237-15240(2002).

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$ 389.00
Cat# AI14029
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