|Other Accession||NM_018697, NP_061167|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Dog|
|Alias Symbol||GPR69B, MGC87139, TASP|
|Other Names||LanC-like protein 2, Testis-specific adriamycin sensitivity protein, LANCL2, GPR69B, TASP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LANCL2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LANCL2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.|
|Cellular Location||Nucleus. Cytoplasm. Cell membrane Note=Localizes to the juxta-nuclear vesicles (PubMed:16979580) Associates with the cortical actin cytoskeleton (PubMed:16979580) Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo (PubMed:16979580). Membrane- association is important for the increased cellular sensitivity to an anticancer drug (adriamycin) (PubMed:16979580)|
|Tissue Location||Expressed in brain and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Mayer H.,et al.DNA Seq. 12:161-166(2001).
Sugimoto Y.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Eley G.D.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
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