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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLSCR3 antibody - middle region   

PLSCR3 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - PLSCR3 antibody - middle region AI14111

    WB Suggested Anti-PLSCR3 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human Placenta
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NRY6
Other Accession NM_020360, NP_065093
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Mouse, Rabbit, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 32kDa
Additional Information
Gene ID 57048
Other Names Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3, PLSCR3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PLSCR3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPLSCR3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Cellular Location Mitochondrion membrane; Single-pass type II membrane protein
Tissue Location Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver
Research Areas
Citations (0)

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Wiedmer T.,et al.Biochim. Biophys. Acta 1467:244-253(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
He Y.,et al.J. Cell. Biochem. 101:1210-1221(2007).

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$ 293.00
Cat# AI14111
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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