|Other Accession||NM_020651, NP_065702|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog|
|Alias Symbol||DKFZp686C18116, MGC50990|
|Other Names||E3 ubiquitin-protein ligase pellino homolog 1, Pellino-1, 6.3.2.-, Peli1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PELI1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PELI1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys- 63'-linked polyubiquitination of IRAK1 allowing subsequent NF- kappa-B activation.|
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Provided below are standard protocols that you may find useful for product applications.
Resch K.,et al.Cytogenet. Cell Genet. 92:172-174(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
Choi K.C.,et al.Nat. Immunol. 7:1057-1065(2006).
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