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WDFY1 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - WDFY1 antibody - N-terminal region AI14126

    WB Suggested Anti-WDFY1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: 721_B cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8IWB7
Other Accession NM_020830, NP_065881
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig
Predicted Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Additional Information
Gene ID 57590
Alias Symbol FENS-1, WDF1, ZFYVE17
Other Names WD repeat and FYVE domain-containing protein 1, FENS-1, Phosphoinositide-binding protein 1, WD40- and FYVE domain-containing protein 1, Zinc finger FYVE domain-containing protein 17, WDFY1, KIAA1435, WDF1, ZFYVE17
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-WDFY1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsWDFY1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDFY1
Function Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436).
Cellular Location Early endosome
Research Areas
Citations (0)
citation

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References

Ridley S.H.,et al.J. Cell Sci. 114:3991-4000(2001).
Hong W.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 7:65-73(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 389.00
Cat# AI14126
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