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Grem1 Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Grem1 Antibody - middle region AI14165

    Host: Rabbit
    Target Name: Grem1
    Sample Tissue: Rat Testis lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35793
Other Accession NM_019282, NP_062155
Reactivity Human, Mouse, Rat, Rabbit, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Additional Information
Gene ID 50566
Alias Symbol Cktsf1b1, drm
Other Names Gremlin-1, Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, Grem1, Cktsf1b1, Drm
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Grem1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGrem1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Grem1
Synonyms Cktsf1b1, Drm
Function Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
Cellular Location Secreted.
Tissue Location Highly expressed in the brain, kidney, spleen, and testis and weakly expressed in the lung and liver Predominantly expressed in differentiated cells as neurons in brain, type I cells in lung and globlet cells in intestine
Citations (0)

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Topol L.Z.,et al.Mol. Cell. Biol. 17:4801-4810(1997).
Chen B.,et al.J. Immunol. 173:5914-5917(2004).

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$ 293.00
Cat# AI14165
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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