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>   home   >   Products   >   Primary Antibodies   >   Pa2g4 antibody - C-terminal region   

Pa2g4 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Pa2g4 antibody - C-terminal region AI14215

    WB Suggested Anti-Pa2g4 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50580
Other Accession NM_011119, NP_035249
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Additional Information
Gene ID 18813
Alias Symbol 38kDa, AA672939, Ebp1, Plfap
Other Names Proliferation-associated protein 2G4, IRES-specific cellular trans-acting factor 45 kDa, ITAF45, Mpp1, Proliferation-associated protein 1, Protein p38-2G4, Pa2g4, Ebp1, Plfap
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Pa2g4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPa2g4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pa2g4
Synonyms Ebp1, Plfap
Function May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly (By similarity). Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). Together with PTBP1 is required for the translation initiation on the foot- and-mouth disease virus (FMDV) IRES. Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).
Cellular Location Isoform 1: Cytoplasm {ECO:0000250|UniProtKB:Q9UQ80}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9UQ80}. Note=Phosphorylation at Ser-361 by PKC/PRKCD regulates its nucleolar localization {ECO:0000250|UniProtKB:Q9UQ80}
Tissue Location Widely expressed.
Citations (0)

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Radomski N.,et al.Exp. Cell Res. 220:434-445(1995).
Nakagawa Y.,et al.Acta Med. Okayama 51:195-206(1997).
Pilipenko E.V.,et al.Genes Dev. 14:2028-2045(2000).
Squatrito M.,et al.Oncogene 23:4454-4465(2004).
Trinidad J.C.,et al.Mol. Cell. Proteomics 5:914-922(2006).

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$ 293.00
Cat# AI14215
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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