Preb Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9WUQ2 |
Other Accession | NM_016703, NP_057912 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45kDa |
Gene ID | 50907 |
---|---|
Alias Symbol | C85705 |
Other Names | Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12, Preb, Sec12 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Preb antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Preb Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Preb |
---|---|
Synonyms | Sec12 |
Function | Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9WTV0}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9WTV0}. Nucleus {ECO:0000250|UniProtKB:Q9WTV0} Note=Concentrates at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) {ECO:0000250|UniProtKB:Q9HCU5} |
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Provided below are standard protocols that you may find useful for product applications.
References
Edgar A.J.,et al.Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
Taylor Clelland C.L.,et al.Genomics 63:391-399(2000).
Weissman J.T.,et al.Traffic 2:465-475(2001).
Sacksteder C.A.,et al.Biochemistry 45:8009-8022(2006).
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