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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CDCA5 antibody - middle region   

CDCA5 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - CDCA5 antibody - middle region AI14270

    WB Suggested Anti-CDCA5 Antibody Titration: 0.2-1 μg/ml
    Positive Control: OVCAR-3 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96FF9
Other Accession NM_080668, NP_542399
Reactivity Human, Mouse, Rabbit, Pig, Bovine, Dog
Predicted Human, Mouse, Rabbit, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 113130
Alias Symbol MGC16386, SORORIN
Other Names Sororin, Cell division cycle-associated protein 5, p35, CDCA5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CDCA5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCDCA5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDCA5
Function Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
Cellular Location Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown
Research Areas
Citations (0)

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Walker M.G.,et al.Curr. Cancer Drug Targets 1:73-83(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Rankin S.,et al.Mol. Cell 18:185-200(2005).
Rankin S.,et al.Mol. Cell 18:609-609(2005).

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$ 293.00
Cat# AI14270
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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