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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Ccnb1ip1 Antibody - N-terminal region   

Ccnb1ip1 Antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Ccnb1ip1 Antibody - N-terminal region AI14293

    Host: Rabbit
    Target Name: Ccnb1ip1
    Sample Tissue: Mouse Thymus lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession D3Z3K2
Other Accession NM_001111119, NP_001104589
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 31kDa
Additional Information
Gene ID 239083
Alias Symbol Gm288, Hei10, mei4
Other Names E3 ubiquitin-protein ligase CCNB1IP1, 6.3.2.-, Cyclin-B1-interacting protein 1, Ccnb1ip1, Gm288, Hei10, Mei4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Ccnb1ip1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCcnb1ip1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ccnb1ip1
Synonyms Gm288, Hei10, Mei4
Function Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over. Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
Cellular Location Nucleus. Chromosome. Note=Associates to the synaptonemal complex
Tissue Location Expressed predominantly in the testes and 17 day embryos (corresponding to prophase I in females). Weakly or not expressed in other tissues.
Research Areas
Citations (0)

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Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ward J.O.,et al.PLoS Genet. 3:E139-E139(2007).
Strong E.R.,et al.Genes (Basel) 1:440-451(2010).
Qiao H.,et al.Nat. Genet. 46:194-199(2014).

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$ 293.00
Cat# AI14293
(40 western blots)
Availability: 2-3 days
Bulk Size
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