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CAPZA3 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - CAPZA3 antibody - N-terminal region AI14312

    WB Suggested Anti-CAPZA3 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: DU145 cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96KX2
Other Accession NM_033328, NP_201585
Reactivity Human, Mouse, Rat, Rabbit, Guinea Pig, Dog
Predicted Rat, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 93661
Alias Symbol CAPPA3, Gsg3
Other Names F-actin-capping protein subunit alpha-3, CapZ alpha-3, CP-alpha-3, Germ cell-specific protein 3, CAPZA3, CAPAA3, GSG3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CAPZA3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCAPZA3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAPZA3
Synonyms CAPAA3, GSG3
Function F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity).
Tissue Location Expressed exclusively in testis and sperm. Highest expression is found in the neck region of ejaculated sperm with lower levels found in the tail and postacrosome region
Research Areas
Citations (0)
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References

Miyagawa Y.,et al.Mol. Hum. Reprod. 8:531-539(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Derivery E.,et al.Dev. Cell 17:712-723(2009).

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$ 389.00
Cat# AI14312
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