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>   home   >   Products   >   Primary Antibodies   >   Eif4e antibody - C-terminal region   

Eif4e antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Eif4e antibody - C-terminal region AI14335

    WB Suggested Anti-Eif4e Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63074
Other Accession NM_053974, NP_446426
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Additional Information
Gene ID 117045
Alias Symbol MGC93265
Other Names Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, Eif4e
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Eif4e antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsEif4e antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Eif4e
Function Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity). Recognizes and binds the 7- methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development.
Cellular Location Cytoplasm, P-body. Cytoplasm
Tissue Location Very high levels in post-meiotic testicular germ cells of rats of reproductive age
Citations (0)

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Miyagi Y.,et al.Lab. Invest. 73:890-898(1995).
Lin T.-A.,et al.Science 266:653-656(1994).

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$ 293.00
Cat# AI14335
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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