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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Nfatc2 antibody - N-terminal region   

Nfatc2 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Nfatc2 antibody - N-terminal region AI14357

    WB Suggested Anti-Nfatc2 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q60591
Other Accession NM_001037178, NP_001032255
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Additional Information
Gene ID 18019
Alias Symbol AI607462, NFAT1, NFAT1-D, Nfatp, NF-ATc2
Other Names Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1, Nfatc2, Nfat1, Nfatp
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Nfatc2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNfatc2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nfatc2
Synonyms Nfat1, Nfatp
Function Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
Cellular Location Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals The subcellular localization of NFATC plays a key role in the regulation of gene transcription
Tissue Location Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas
Research Areas
Citations (0)

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McCaffrey P.G.,et al.Science 262:750-754(1993).
Luo C.,et al.Mol. Cell. Biol. 16:3955-3966(1996).
Plyte S.,et al.J. Biol. Chem. 276:14350-14358(2001).
Vihma H.,et al.Genomics 92:279-291(2008).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).

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$ 293.00
Cat# AI14357
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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