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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Psenen antibody - N-terminal region   

Psenen antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Psenen antibody - N-terminal region AI14395

    WB Suggested Anti-Psenen Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9CQR7
Other Accession NM_025498, NP_079774
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 12kDa
Additional Information
Gene ID 66340
Alias Symbol 1700023M09Rik, MGC102026
Other Names Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, Psenen, Pen2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Psenen antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPsenen antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Psenen
Synonyms Pen2
Function Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
Research Areas
Citations (0)

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Carninci P.,et al.Science 309:1559-1563(2005).

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$ 293.00
Cat# AI14395
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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