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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Scg3 antibody - C-terminal region   

Scg3 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Scg3 antibody - C-terminal region AI14397

    WB Suggested Anti-Scg3 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Small Intestine
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47867
Other Accession NM_001164790, NP_001158262
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Additional Information
Alias Symbol 1B1075, AI385542, Chgd, SgIII
Other Names Secretogranin-3, Secretogranin III, SgIII, Scg3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Scg3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsScg3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Scg3
Cellular Location Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts in intragranular conditions. In neuroblastoma cells, colocalizes with PMCH, NPY, POMC and orexin/HCRT in secretory granules
Tissue Location Expressed in various brain areas, with highest levels in the arcuate nucleus and the lateral hypothalamic area, as well as the paraventricular nucleus and the ventromedial hypothalamus (at protein level). EMBL; U02982; AAA56636.1; -; mRNA EMBL; AK133655; BAE21767.1; -; mRNA EMBL; AK139140; BAE23899.1; -; mRNA EMBL; AK158315; BAE34456.1; -; mRNA EMBL; AK164089; BAE37620.1; -; mRNA EMBL; CH466522; EDL26334.1; -; Genomic_DNA EMBL; BC024785; AAH24785.1; -; mRNA CCDS; CCDS23347.1; -. [P47867-1] RefSeq; NP_001158262.1; NM_001164790.1. [P47867-2] RefSeq; NP_033156.1; NM_009130.3. [P47867-1] UniGene; Mm.2386; - ProteinModelPortal; P47867; - SMR; P47867; - STRING; 10090.ENSMUSP00000034699; - iPTMnet; P47867; - PhosphoSitePlus; P47867; - PaxDb; P47867; - PeptideAtlas; P47867; - PRIDE; P47867; - Ensembl; ENSMUST00000034699; ENSMUSP00000034699; ENSMUSG00000032181. [P47867-1] GeneID; 20255; - KEGG; mmu:20255; - UCSC; uc009qss.2; mouse. [P47867-1] UCSC; uc009qst.2; mouse. [P47867-2] CTD; 29106; - MGI; MGI:103032; Scg3 eggNOG; ENOG410IHUH; Eukaryota eggNOG; ENOG4110KQ3; LUCA GeneTree; ENSGT00390000005488; - HOGENOM; HOG000247064; - HOVERGEN; HBG057085; - InParanoid; P47867; - OMA; ENKPGQS; - OrthoDB; EOG091G06X3; - PhylomeDB; P47867; - TreeFam; TF331266; - Reactome; R-MMU-114608; Platelet degranulation PRO; PR:P47867; - Proteomes; UP000000589; Chromosome 9 Bgee; ENSMUSG00000032181; - CleanEx; MM_SCG3; - Genevisible; P47867; MM GO; GO:0031410; C:cytoplasmic vesicle; IBA:GO_Central GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell GO; GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell GO; GO:0044822; F:poly(A) RNA binding; ISO:MGI InterPro; IPR026197; SCG3 PANTHER; PTHR17388; PTHR17388; 1 Pfam; PF15467; SGIII; 1 1: Evidence at protein level; Alternative splicing; Cleavage on pair of basic residues; Complete proteome; Cytoplasmic vesicle; Membrane; Phosphoprotein; Reference proteome; Secreted; Signal SIGNAL 1 22 CHAIN 23 471 Secretogranin-3 /FTId=PRO_0000005462 MOD_RES 40 40 Phosphoserine MOD_RES 365 365 Phosphoserine VAR_SEQ 355 360 SKLFPA -> T (in isoform 2) /FTId=VSP_042877 SEQUENCE 471 AA; 53326 MW; FC1E9C381AFCA564 CRC64; MGFLWTGSWI LVLVLNSGPI QAFPKPEGSQ DKSLHNRELS AERPLNEQIA EAEADKIKKA FPSESKPSES NYSSVDNLNL LRAITEKETV EKERQSIRSP PFDNQLNVED ADSTKNRKLI DEYDSTKSGL DHKFQDDPDG LHQLDGTPLT AEDIVHKIAT RIYEENDRGV FDKIVSKLLN LGLITESQAH TLEDEVAEAL QKLISKEANN YEETLDKPTS RTENQDGKIP EKVTPVAAVQ DGFTNRENDE TVSNTLTLSN GLERRTNPHR EDDFEELQYF PNFYALLTSI DSEKEAKEKE TLITIMKTLI DFVKMMVKYG TISPEEGVSY LENLDETIAL QTKNKLEKNT TDSKSKLFPA PPEKSQEETD STKEEAAKME KEYGSLKDST KDDNSNLGGK TDEATGKTEA YLEAIRKNIE WLKKHNKKGN KEDYDLSKMR DFINQQADAY VEKGILDKEE ANAIKRIYSS L
Research Areas
Citations (0)

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Dopazo A.,et al.J. Mol. Neurosci. 4:225-233(1993).
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hosaka M.,et al.Mol. Biol. Cell 13:3388-3399(2002).
Tanabe A.,et al.J. Clin. Endocrinol. Metab. 92:1145-1154(2007).

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$ 293.00
Cat# AI14397
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