|Other Accession||NM_001164790, NP_001158262|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||1B1075, AI385542, Chgd, SgIII|
|Other Names||Secretogranin-3, Secretogranin III, SgIII, Scg3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Scg3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Scg3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts in intragranular conditions. In neuroblastoma cells, colocalizes with PMCH, NPY, POMC and orexin/HCRT in secretory granules|
|Tissue Location||Expressed in various brain areas, with highest levels in the arcuate nucleus and the lateral hypothalamic area, as well as the paraventricular nucleus and the ventromedial hypothalamus (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Dopazo A.,et al.J. Mol. Neurosci. 4:225-233(1993).
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hosaka M.,et al.Mol. Biol. Cell 13:3388-3399(2002).
Tanabe A.,et al.J. Clin. Endocrinol. Metab. 92:1145-1154(2007).
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