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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Rnls antibody - middle region   

Rnls antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Rnls antibody - middle region AI14427

    WB Suggested Anti-Rnls Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
  • WB - Rnls antibody - middle region AI14427

    WB Suggested Anti-Rnls Antibody
    Positive Control: Lane 1: 40ug Mouse liver tissue lysate Lane 2: 40ug Mouse liver tissue lysate
    Primary Antibody Dilution : 1:500
    Secondary Antibody : Anti-rabbit-HRP
    Secondry Antibody Dilution : 1:2500
    Submitted by: Nitish R Mahapatra, IIT Madras
  • WB - Rnls antibody - middle region AI14427

    WB Suggested Anti-Rnls Antibody
    Positive Control: Lane 1: 40ug Mouse kidney tissue lysate Lane 2: 40ug Mouse kidney tissue lysate
    Primary Antibody Dilution : 1:500
    Secondary Antibody : Anti-rabbit-HRP
    Secondry Antibody Dilution : 1:2500
    Submitted by: Nitish R Mahapatra, IIT Madras
  • WB - Rnls antibody - middle region AI14427

    WB Suggested Anti-Rnls Antibody
    Positive Control: Lane 1: 40ug Mouse N2a cell lysate
    Lane 2: 40ug Mouse N2a cell lysate

    Primary Antibody Dilution : 1:500
    Secondary Antibody : Anti-rabbit-HRP
    Secondry Antibody Dilution : 1:2500
    Submitted by: Nitish R Mahapatra, IIT Madras
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession A7RDN6
Other Accession NM_001167818, NP_001161290
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 67795
Alias Symbol 6530404N21Rik, AI452315, AW060440, C10orf59
Other Names Renalase, 1.6.3.5, Monoamine oxidase-C, MAO-C, mMAO-C, alpha-NAD(P)H oxidase/anomerase, Rnls {ECO:0000312|MGI:MGI:1915045}
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rnls antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRnls antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rnls {ECO:0000312|MGI:MGI:1915045}
Function Catalyzes the oxidation of the less abundant 1,2- dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta- NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Cellular Location Secreted.
Tissue Location Expressed predominantly in kidney and testis with lower levels in liver, heart and embryo and weak expression in brain and skeletal muscle.
Research Areas
Citations (0)

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References

Wang J.,et al.Mol. Biol. Rep. 35:613-620(2008).
Carninci P.,et al.Science 309:1559-1563(2005).

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$ 293.00
Cat# AI14427
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