|Other Accession||NM_000132, NP_000123|
|Reactivity||Human, Rabbit, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Rabbit, Sheep, Horse, Bovine|
|Alias Symbol||AHF, DXS1253E, F8B, F8C, FVIII, HEMA|
|Other Names||Coagulation factor VIII, Antihemophilic factor, AHF, Procoagulant component, Factor VIIIa heavy chain, 200 kDa isoform, Factor VIIIa heavy chain, 92 kDa isoform, Factor VIII B chain, Factor VIIIa light chain, F8, F8C|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-F8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||F8 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.|
|Cellular Location||Secreted, extracellular space.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Truett M.A.,et al.DNA 4:333-349(1985).
Wood W.I.,et al.Nature 312:330-337(1984).
Levinson B.,et al.Genomics 14:585-589(1992).
Toole J.J.,et al.Nature 312:342-347(1984).
Gitschier J.,et al.Hum. Mol. Genet. 1:199-200(1992).
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