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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HSH2D antibody - C-terminal region   

HSH2D antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - HSH2D antibody - C-terminal region AI14546

    WB Suggested Anti-HSH2D Antibody Titration: 1.0 μg/ml
    Positive Control: COLO205 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96JZ2
Other Accession NM_032855, NP_116244
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 39kDa
Additional Information
Gene ID 84941
Alias Symbol ALX, FLJ14886, HSH2
Other Names Hematopoietic SH2 domain-containing protein, Hematopoietic SH2 protein, Adaptor in lymphocytes of unknown function X, HSH2D, ALX
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HSH2D antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHSH2D antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSH2D
Synonyms ALX
Function May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.
Research Areas
Citations (0)

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Oda T.,et al.Biochem. Biophys. Res. Commun. 288:1078-1086(2001).
Greene T.A.,et al.J. Biol. Chem. 278:45128-45134(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI14546
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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