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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ACER1 antibody - C-terminal region   

ACER1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - ACER1 antibody - C-terminal region AI14573

    WB Suggested Anti-ACER1 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TDN7
Other Accession NM_133492, NP_597999
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 31kDa
Additional Information
Gene ID 125981
Alias Symbol ASAH3, MGC138327, MGC138329, ALKCDase1
Other Names Alkaline ceramidase 1, AlkCDase 1, Alkaline CDase 1,, Acylsphingosine deacylase 3, N-acylsphingosine amidohydrolase 3, ACER1, ASAH3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ACER1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsACER1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACER1
Synonyms ASAH3
Function Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo- phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Mainly expressed in epidermis.
Research Areas
Citations (0)

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Mao C.,et al.J. Biol. Chem. 278:31184-31191(2003).
Houben E.,et al.J. Lipid Res. 47:1063-1070(2006).

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$ 293.00
Cat# AI14573
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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