|Other Accession||NM_024551, NP_078827|
|Reactivity||Human, Mouse, Rat, Rabbit, Goat, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||ACDCR2, FLJ21432, MGC4640, PAQR2|
|Other Names||Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ADIPOR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ADIPOR2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.|
|Cellular Location||Membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles|
|Tissue Location||Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung|
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Provided below are standard protocols that you may find useful for product applications.
Tang Y.T.,et al.J. Mol. Evol. 61:372-380(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yamauchi T.,et al.Nature 423:762-769(2003).
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