|Other Accession||NM_000583, NP_000574|
|Reactivity||Human, Rat, Pig, Horse|
|Predicted||Human, Rat, Horse|
|Alias Symbol||DBP, DBP/GC, GRD3, VDBG, VDBP|
|Other Names||Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-GC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||GC antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Cooke N.E.,et al.J. Clin. Invest. 76:2420-2424(1985).
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998(1985).
Braun A.,et al.Biochim. Biophys. Acta 1216:385-394(1993).
Witke W.F.,et al.Genomics 16:751-754(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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