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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rab5a antibody - middle region   

Rab5a antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Rab5a antibody - middle region AI14627

    WB Suggested Anti-Rab5a Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9CQD1
Other Accession NM_025887, NP_080163
Reactivity Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Sheep, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 24kDa
Additional Information
Gene ID 271457
Alias Symbol 2410015H04Rik, AI663973, AU021172
Other Names Ras-related protein Rab-5A, Rab5a, nnyRab5a
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rab5a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRab5a antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rab5a
Synonyms nnyRab5a
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension (By similarity).
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Note=Alternates between membrane-bound and cytosolic forms.
Research Areas
Citations (0)

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Kuroda T.S.,et al.J. Biol. Chem. 277:9212-9218(2002).
Itoh T.,et al.Genes Cells 11:1023-1037(2006).
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (APR-2007) to UniProtKB.

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$ 293.00
Cat# AI14627
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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