|Other Accession||NM_001570, NP_001561|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig|
|Alias Symbol||IRAK-2, MGC150550|
|Other Names||Interleukin-1 receptor-associated kinase-like 2, IRAK-2, IRAK2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-IRAK2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||IRAK2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.|
|Tissue Location||Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Rosati O.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzio M.,et al.Science 278:1612-1615(1997).
Wesche H.,et al.J. Biol. Chem. 274:19403-19410(1999).
Lin S.-C.,et al.Nature 465:885-890(2010).
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